Other Smith-Waterman implementations on Cell/BE Michael Farrar, None 19 January 2009 The SWPS3 is not the only Smith-Waterman implementation for the Cell Broadband Engine (Cell BE). While this implementations does handle longer sequences, greater than 3000, which other implementations were not able to handle , it is not the fastest reported. Two papers report a faster implementation. This first is a paper  describing an Alpern implementation running on a PS3. This paper reports speeds approaching 9 GCUPS while able to handle sequences of 3000 residues in length. For optimal performance, the sequence database first needs to be sorted by sequence length.Another paper  describes the port of the Striped Smith-Waterman to the Cell BE. This port achieves speeds of 12 GCUPS on a PS3 and is able to handle sequences of 32,000 residues. Sachdeva, V., Kistler, M., Speight, E. and Tzeng, T. K. (2007) Exploring the Viability of the Cell Broadband Engine for Bioinformatics Applications. In Proceedings of the 21st IEEE International Parallel and Distributed processing Symposium: Long Beach, California, March 26-30, 2007.http://www.hicomb.org/HiCOMB2007/proceedings.html. Accessed 2008 Sep 18. Rudnicki, W. R., Jankowski, A., Modzelewski, A., Piotrowski, A. and Zadrozny, A. (2008) Efficient implementation of the Smith Waterman algorithm on Cell processor. In Bioinformatics 2008 Conference: Warsaw, Poland, April 24-27, 2008.https://bioinformatics2008.icm.edu.pl/web/guest/abstracts. Accessed 2008 Sep 18. Wirawan, A., Kwoh, C. K., Hieu, N. T., and Schmidt, B. (2008) CBESW: Sequence Alignment on the Playstation 3. BMC Bioinformatics 9, 377.http://www.biomedcentral.com/1471-2105/9/377. Accessed 2008 Nov 2. Farrar, M. S. (2008) Optimizing Smith-Waterman for the Cell Broadband Engine.http://farrar.michael.googlepages.com/smith-watermanfortheibmcellbe. Accessed 2008 Sep 18. Competing interests Competing interests:Author of "Optimizing Smith-Waterman for the Cell Broadband Engine" and "Striped Smith–Waterman speeds database searches six times over other SIMD implementations"