Figure 1

CD44 exon v3. A) Genomic structure of human CD44 gene (gray boxes, constitutive exons; white boxes, alternative exons; black box, variable exon v3; black line, introns). B) Schematic representation of exon v3 and its flanking introns (gray boxes, relative location of the XX and Y splicing enhancer motifs; white box, relative location of the nucleotides coding for the GAG binding site and the SGSG motif). Genomic DNA amplification was performed with PCR primers located in intron 6 and in the v3-intron 7 junction (indicated by arrows).