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Table 1 Power of MDR (from Ritchie et al. 2003) to detect correct functional epistatic loci.

From: Power of grammatical evolution neural networks to detect gene-gene interactions in the presence of error

Source of Noise

Power (%)

 

Model 1

Model 2

Model 3

Model 4

Model 5

Model 6

None

100

100

99

99

82

84

GE

100

100

100

97

80

92

GH

3

41

2

3

4

4

PC

90

99

45

32

30

32

MS

100

100

99

97

82

87

GE+GH

4

41

2

3

4

6

GE+PC

94

99

41

48

28

33

GE+MS

100

100

98

98

74

84

GH+PC

0

1

0

0

0

0

GH+MS

5

38

0

2

4

6

PC+MS

96

99

42

43

14

16

GE+GH+PC

1

1

0

0

0

0

GE+GH+MS

6

34

2

1

3

7

GH+PC+MS

0

0

0

0

0

0

GE+PC+MS

94

100

48

42

18

16

GE+GH+PC+MS

0

1

0

1

0

0

  1. GE = 5% Genotyping Error; GH = 50% Genetic Heterogeneity; PC = 50% Phenocopy; MS = 5% Missing Data