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Figure 1 | BMC Research Notes

Figure 1

From: Suppression of MMP activity in bovine cartilage explants cultures has little if any effect on the release of aggrecanase-derived aggrecan fragments

Figure 1

Epitope-specificity of monoclonal antibodies binding to aggrecan fragments. Schematic representation of the monoclonal antibodies selected for incorporation into immunoassays for quantification of aggrecan fragments carrying neo-epitopes. MAb F78 recognises a repeated epitope in the G1 and G2 domain, MAb AF28 binds to the MMP-derived neo-epitope 342FFGFG, MAb 1H11 binds the neo-epitope NITEGE373, and MAb 6D6 binds to 374ARGSV.

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