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Table 3 Some epistatic interactions identified by AntEpiSeeker on WTCCC RA data.

From: AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm

Epistatic interactions

Location

Related genes

P value

(rs6457617, rs41443144)

6p21.32-6p25.1

MHC, RP3

<10-16

(rs743777, rs9627642)

22q12.3-22q13.31

NR, NR

< 10-16

(rs2837960, rs41492246)

21q22.3-21q22.12

NR, NR

< 10-16

(rs6920220, rs17165379)

6q23.3-6p25.3

TNFAIP3, NR

< 10-16

(rs6457620, rs41454544)

6p21.32-6q21

HLA-DRB1, OSTM1

< 10-16

(rs3890745, rs41348151)

1p36.32-1p21.3

MMEL1, NR

< 10-16

(rs4810485, rs2748666)

20q13.12-20q11.23

CD40, NR

< 10-16