Figure 1

Alignment of the sequences of human calmodulin, CaBPs and calneuron proteins. Protein sequences were compiled and aligned using ClustalW. Residues that are identical in more than one protein are highlighted in red and residues with similar properties are highlighted in blue. The lines above the sequences indicate the position of the predicted 12 amino acid coordinating loop within the EF-hands The green bar beneath the sequence indicates the position of the linker region in the CaBPs that is extended in comparison to calmodulin.