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Figure 1 | BMC Research Notes

Figure 1

From: Using GeneReg to construct time delay gene regulatory networks

Figure 1

The forward selection of regulators in time delay linear regression model. The selected regulator set with m regulators is defined as the S indexes of regulators in Ωs are The to-be-selected regulator set with n regulators is defined as and the S indexes of regulators in Ω t are In the forward selection procedure, each regulator in Ω t will be successively tested whether it can be added into Ω s . During each test process, the time delays of Ω s are held the same. All possible time delays of the regulator in Ω t with smallest S index that is are traversed, and the time delay of which achieves the smallest AIC of is considered as the optimal time delay of . This smallest AIC of is then compared with the AIC of original . If wil be moved from Ω t to Ω s . Otherwise, will be eliminated from Ω t . In next round, the new regulator in Ω t with smallest S index will be tested until Ω t is empty.

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