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Figure 4 | BMC Research Notes

Figure 4

From: Characterization of voltage-gated ionic currents in a peripheral sensory neuron in larval Drosophila

Figure 4

Larval dbds express voltage gated Na+ channels. A) Typical Na+ current trace evoked by depolarizing voltage steps. B) Voltage clamp step protocol. Currents are evoked from voltage steps between -80 mV to +60 mV in increments of 10 mV. For clarity, 20 mV increments are shown in (A, B). The voltage step protocol is preceded by a -90 mV pre-pulse to remove any inactivating components. C) Normalized I-V relationship of I Na . The channels begin activating between -50 and -40 mV and peak at -30 to -20 mV. Data plotted as mean ± SEM. External solution contains 4-AP (10 mM), TEA (50 mM) and 0 mM Ca2+. Internal solution contains cesium (5 mM).

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