Table 1 Number of adverse drug reactions reported for psychotropic medication in the paediatric population by age and seriousness (in italic) (1998 to 2007)
Age groups (years) | <1 | 1<2 | 2-10 | 11<17 | Total |
|---|---|---|---|---|---|
Antipsychotics (N05A) | Â | Â | Â | Â | Â |
Levomepromazine | 1 (1) | 0 | 0 | 1 | 2 (1) |
Zipradison | 0 | 0 | 2 | 16 (11) | 18 (11) |
Zuclopenthixol | 1 (1) | 0 | 0 | 1 (1) | 2 (2) |
Chlorprothixene | 0 | 0 | 0 | 2 | 2 |
Clozapine | 0 | 0 | 0 | 1 | 1 |
Olanzapine | 8 (8) | 5 (5) | 0 | 11 (3) | 24 (16) |
Quetiapine | 1 (1) | 0 | 1 (1) | 14 (12) | 16 (14) |
Sulpiride | 0 | 0 | 0 | 3 | 3 |
Risperidone | 1 (1) | 0 | 5 | 18 (5) | 24 (6) |
Aripiprazol | 0 | 0 | 0 | 14 (3) | 14 (3) |
Total | 12 (12) | 5 (5) | 8 (1) | 81 (35) | 106 (53) |
Hypnotics and sedatives (N05B/N05C) | Â | Â | Â | Â | Â |
Diazepam | 1 (1) | 0 | 0 | 0 | 1 (1) |
Oxazepam | 3 (3) | 0 | 0 | 0 | 3 (3) |
Buspirone | 1 (1) | 0 | 0 | 0 | 1 (1) |
Chloral hydrate | 0 | 0 | 3 (3) | 0 | 3 (3) |
Midazolam | 0 | 0 | 1 (1) | 2 (2) | 3 (3) |
Total | 5 (5) | 0 | 4 (4) | 2 (2) | 11 (11) |
Antidepressants (N06A) | Â | Â | Â | Â | Â |
Imipramine | 0 | 0 | 1 (1) | 0 | 1 (1) |
Clomipramine | 1 (1) | 0 | 0 | 0 | 1 (1) |
Amitriptyline | 2 (2) | 0 | 0 | 0 | 2 (2) |
Fluoxetine | 14 (14) | 0 | 0 | 1 (1) | 15 (15) |
Citalopram | 17 (17) | 4 (4) | 5 (2) | 10 (6) | 36 (29) |
Paroxetine | 5 (4) | 0 | 0 | 6 (2) | 11 (6) |
Sertralin | 11 (11) | 0 | 9 (3) | 25 (20) | 45 (34) |
Escitalopram | 1 (1) | 1 (1) | 0 | 0 | 2 (2) |
Oxitriptan | 0 | 0 | 0 | 3 | 3 |
Mirtazapin | 1 (1) | 0 | 0 | 12 (8) | 13 (9) |
Venlafaxin | 1 (1) | 0 | 0 | 3 | 4 (1) |
Total | 53 (52) | 5 (5) | 15 (6) | 60 (37) | 133 (100) |
Psychostimulants (N06B) | Â | Â | Â | Â | Â |
Methylphenidate | 0 | 0 | 85 (35) | 44 (17) | 129 (52) |
Modafinil | 0 | 0 | 0 | 7 (7) | 7 (7) |
Atomoxetine | 0 | 0 | 23 (7) | 20 (11) | 43 (18) |
Total | 0 | 0 | 108 (42) | 71 (35) | 179 (77) |
Total N05 and N06 | 70 (69) | 10 (10) | 135 (53) | 214 (109) | 429 (241) |