From: The dynamics of E1A in regulating networks and canonical pathways in quiescent cells
Accession | Gene Symbol | Description | E2F4 binding 1,2 | Zcut | glog(FC) |
---|---|---|---|---|---|
 |  | DNA repair processes: homologous recombination, mismatch/excision repair, and non-homologous end-joining |  |  |  |
NM_007499.1 | ATM | Ataxia telangiectasia mutated | + | 7.498 | 0.585 |
NM_007550 | BLM | Bloom syndrome, RecQ helicase-like | + | 20.559 | 1.529 |
NM_009764.2 | BRCA1 | Breast cancer 1, early onset | - | 4.757 | 0.381 |
NM_009765.1 | BRCA2 | Breast cancer 2, early onset | - | 12.234 | 0.927 |
NM_007691.2 NM_009863.1 | CHEK1 CDC7 | CHK1 checkpoint homolog (S. Pombe) Cell division cycle 7 homolog (S. cerevisiae) | + + | 3.202 17.694 | 0.261 1.321 |
NM_028119.2 | DDB2 | Damage-specific DNA binding protein 2, 48 kDa | + | 9.204 | 0.709 |
NM_177752.2 | EME1 | Essential meiotic endonuclease 1 homolog 1 (S. pombe) | - | 2.820 | 0.232 |
NM_001033244.1 | FANCD2 | Fanconi anemia, complementation group D2 | + | 9.508 | 0.730 |
NM_007999.2 | FEN1 | Flap structure-specific endonucleae 1 | + | 8.577 | 1.957 |
NM_010436.2 | H2AFX | H2A histone family, member X | + | 4.634 | 1.095 |
NM_010715.1 | LIG1 | Ligase 1, DNA, ATP-dependent | + | 18.060 | 1.348 |
NM_026810.1 | MLH1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | + | 2.794 | 0.230 |
NM_018736.2 | MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | - | 5.432 | 0.432 |
NM_008628.1 | MSH2 | MutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | + | 3.107 | 0.254 |
NM_010830.1 | MSH6 | MutS homolog 6 (E.coli) | - | 13.241 | 1.000 |
NM_013752 | NBN | Nibrin | - | 8.326 | 0.645 |
NM_009632.2 | PARP2 | Poly (ADP-ribose) polymerase 2 | + | 7.656 | 0.596 |
NM_011045.1 | PCNA | Proliferating cell nuclear antigen | + | 10.999 | 0.838 |
NM_008886.1 | PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | - | 8.409 | 0.651 |
NM_011131.2 | POLD1 | Polymerase (DNA directed) delta 1, catalytic subunit 125 kDa | + | 7.744 | 0.603 |
NM_030715.2 NM_008949.2 | POLH PSMC3IP | Polymerase (DNA directed), eta PSMC3 interacting protein | - + | 3.448 17.496 | 0.825 1.307 |
NM_013917.1 NM_021385.1 | PTTG1 RAD18 | Pituitary tumor-transforming 1 RAD18 homolog (S. cerevisiae) | + + | 7.190 7.629 | 0.562 0.594 |
NM_009012.1 | RAD50 | RAD50 homolog (S. cerevisiae) | + | 4.064 | 0.328 |
NM_011234.2 | RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | + | 12.514 | 0.947 |
NM_009013.1 | RAD51AP1 | RAD51 associated protein 1 | + | 9.638 | 0.740 |
NM_009015.2 | RAD54L | RAD54-like (S. cerevisiae) | + | 9.320 | 2.115 |
NM_026653.1 | RPA1 | Replication protein A1, 70 kDa | - | 9.177 | 0.707 |
NM_011237.1 | RAD9A | RAD9A homolog A | - | 4.501 | 0.361 |
NM_023042.1 | RECQL | RecQ protein-like (DNA helicase Q1-like) | + | 5.724 | 0.125 |
NM_021419.1 | RNF8 | Ringfinger protein 8 | + | 2.663 | 0.222 |
NM_011677.1 | UNG | Uracil-DNA glycosylase | + | 4.901 | 0.475 |
NM_133786.3 NM_153808.1 | SMC4L1 SMC5L1 | Structural maintenance of chromosomes four-like 1 Structural maintenance of chromosomes five-like 1 | - - | 4.290 10.047 | 0.345 0.769 |
XM_127444.3 NM_010247.1 | TRIP13 XRCC6 | Thyroid hormone receptor interactor 13 X-ray repair complementing defective repair in Chinese hamster | + - | 3.630 3.039 | 0.294 0.732 |
Accession | Gene Symbol | Description | E2F4 binding 1,2 | Zcut | glog(FC) |
 |  | DNA damage response |  |  |  |
NM_007499.1 | ATM | Ataxia telangiectasia mutated | + | 7.498 | 0.585 |
NM_009764.2 | BRCA1 | Breast cancer 1, early onset | - | 4.757 | 0.381 |
NM_009765.1 | BRCA2 | Breast cancer 2, early onset | - | 12.234 | 0.927 |
NM_007691.2 | CHEK1 | CHK1 checkpoint homolog (S. Pombe) | + | 3.202 | 0.261 |
NM_001033244.1 | FANCD2 | Fanconi anemia, complementation group D2 | + | 9.508 | 0.730 |
NM_008316.2 | HUS1 | HUS1 checkpoint homolog (S. pombe) | - | 4.438 | 0.357 |
NM_010774.1 | MBD4 | Methyl-CpG binding domain protein 4 | - | 8.816 | 0.681 |
NM_008583.1 | MEN1 | Multiple endocrine neoplasia 1 | ? | 4.995 | 0.399 |
NM_026810.1 | MLH1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | + | 2.794 | 0.230 |
NM_008628.1 | MSH2 | MutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | + | 3.107 | 0.254 |
NM_010830.1 | MSH6 | Muts homolog 6 (E. coli) | - | 13.241 | 1.000 |
NM_008884.2 | PML | Promyelocytic leukemia | - | 3.155 | 0.257 |
NM_011237.1 | RAD9A | RAD9 homolog A (S. pombe) | - | 4.501 | 0.361 |
NM_011234.2 | RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | + | 12.514 | 0.947 |
NM_009015.2 | RAD54L | RAD54-like (S. cerevisiae) | + | 9.320 | 2.115 |
NM_026653.1 | RPA1 | Replicaton protein A1, 70 kDa | + | 9.177 | 0.707 |
NM_011623.1 | TOP2A | Topoisomerase (DNA) 11 alpha 170 kDa | + | 8.224 | 1.880 |
NM_011640.1 | TP53 | Tumor protein p53 | - | 6.333 | 0.499 |
NM_010247.1 | XRCC6 | X-ray repair complementing defective repair in Chinese hamster | - | 3.039 | 0.732 |
Accession | Gene Symbol | Description | E2F4 binding 1,2 | Zcut | glog(FC) |
 |  | DNA replication checkpoints and checkpoint control |  |  |  |
NM_007499.1 | ATM | Ataxia telangiectasia mutated | + | 7.498 | 0.585 |
NM_026014.3 | CDT1 | Chromatin licensing and DNA replication factor 1 | - | 4.137 | 0.983 |
NM_007691.2 NM_008316.2 | CHEK1 HUS1 | CHK1 checkpoint homolog (S. Pombe) HUS1, checkpoint homolog (S. pombe) | + + | 3.202 4.438 | 0.261 0.357 |
NM_008583.1 | MEN1 | Multiple endocrine neoplasia 1 | - | 4.995 | 0.399 |
NM_008628.1 | MSH2 | MutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | + | 3.107 | 0.254 |
NM_134092.2 | MTBP | Mdm2, transformed 3T3 cell double minute 2 | + | 9.084 | 0.700 |
NM_011237.1 | RAD9A | RAD9 homolog A (S. pombe) | + | 4.501 | 0.361 |
NM_011640.1 | TP53 | Tumor protein p53 | - | 6.333 | 0.499 |