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Table 4 Characteristics of patients that did and did not presented adverse drug reactions (ADRs)

From: The study of vancomycin use and its adverse reactions associated to patients of a brazilian university hospital

Characteristics

 

Patients ADR +

 

Patients ADR -

 

Median

Mean

95%CI(%)

Median

Mean

95% CI(%)

Age (years)

47

49.1

42.0 - 56.3

52

51.1

47.3 - 55.0

Treatment time (days)

7.0

11.6

7.7 - 15.5

7.0

9.0

7.1 - 10.9

Total Vancomycin dose (g)

8.0

23.3

6.5 - 40.1

8.0

16.2

11.2 - 21.2

Vancomycin Daily dose (g/day)

1.4

2.0

1.1-2.8

1.0

1.9

1.5-2.4

Initial creatinine (mg/dl)

1.1

1.7

1.1 - 2.3

1.0

2.1

1.5 - 2.8

Albumin (g/dl)

1.4

1.9

1.6 - 2.1

1.75

1.9

1.6 - 2.1

  1. Statistical analysis was performed using z-test. P > 0.05 for all the parameters evaluated comparing patients ADR + and -.