| Concentration | Viability (%) |
---|
36 h cultured Mϕ | - | 95.8 ± 1.5 |
Prednisone | 10-6 M | 84.2 ± 2.5 |
| 10-8 M | 86.1 ± 1.7 |
Thalidomide | 10-6 M | 85.4 ± 3.2 |
| 10-8 M | 86.9 ± 2.2 |
Cyclosporine A | 10-6 M | 85.5 ± 2.3 |
| 10-8 M | 88.2 ± 3.7 |
Amitriptyline | 10-6 M | 83.8 ± 2.9 |
| 10-8 M | 87.7 ± 0.8 |
- aPurified MΦ were first pre-incubated for 24 h with 10 ng/ml LPS, and then cultured for 36 h in the presence or absence of 10-6 M or 10-8 M prednisone, thalidomide, cyclosporine A, or amitriptyline. Cell viability was then assessed using propidium iodide. All results are shown as mean ± SD for three independent experiments, which did not vary significantly from the control.