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Table 2 Measurements in blood sample in the Taiwan Birth Panel Study

From: The Taiwan Birth Panel Study: a prospective cohort study for environmentally- related child health

   Environmental exposures

Specimen

Measures

   Smoking

Maternal and cord blood

Cotinine

   Heavy metals [25–27]

Maternal and cord blood

Pb, As, Hg, Cd, Be, Sb, Ba, Ce, Pt, Th, Mn, Zn, Cu, Se, Co, Ga, Mo, U

   Perfluorinated chemicals

Cord blood

PFHxA, PFHpA, PFHxS, PFOA, PFOS, PFNA, PFDeA, PFUA, Me-PFOSA-AcOH, Et-PFOSA-AcOH, PFOSA, PFDoA

   Non-persistent pesticides

Cord blood

Organophosphates: chlorpyrifos.

Pyrethroids: cypermethrin, flucythrinate.

Diseases

  

   Atopic diseases [23, 24]

Maternal, cord blood and child blood at age 2

IgE

 

Maternal and cord blood

NGF,VIP

   Infection [30, 31]

Maternal and cord blood

IgM & IgG of toxoplasmosis and cytomegalovirus

Genotyping

  

Single-nucleotide polymorphisms

  

   Smoking [21, 22]

Maternal and cord blood DNA

CYP1A1 Msp1, CYP1A1 Ile462Val, GSTT1, GSTM1, GSTP1

   Pesticides

Maternal and cord blood DNA

Paraoxonase-1 (PON1) L55M, paraoxonase-1 (PON1) Q192R, paraoxonase-1 (PON1) C(-162)T

   Mercury

Cord blood DNA

Apolipoprotein E (APOE)

   Manganese

Cord blood DNA

Manganese superoxide dismutase 2 (MnSOD2)

   Lead

Cord blood DNA

Vitamin D receptor BsmI (VDR BsmI), Vitamin D receptor FokI (VDR FokI), δ-aminolevulinic acid dehydratase (ALAD)

   DNA methylation

Cord blood DNA

Illumina methylation array