Figure 1
From: The plausible reason why the length of 5' untranslated region is unrelated to organismal complexity
Logical connections between the elongation of 5'UTR and the increase in organismal complexity. The boxes are the biological characteristics that are suggested to be associated with each other, as represented by two-way arrows (i)~(v). Connection (i): longer 5'UTRs - more genes with tissue-specific expression pattern (less breadth); Connection (ii): more genes with tissue-specific expression pattern - higher organismal complexity; Connection (iii): longer 5'UTRs - more uAUGs/uORFs (upstream start codons/upstream open reading frames); Connection (iv): more uAUGs/uORFs (higher complexity in translational regulations) - higher organismal complexity; Connection (v): longer 5'UTRs - higher organismal complexity.