Figure 5From: A model-based circular binary segmentation algorithm for the analysis of array CGH dataThe comparison of ROC curves between the hybrid CBS and eCBS. The ROC curves obtained from the segmentation results of 10,000 simulated datasets. Each dataset contained 1,500 probes. Case 1 refers to the performance of analyzing normally distributed data with sk = 0, ku = 3. Case 2 refers to the performance of analyzing mildly skewed and heavy-tailed data with sk = 0.2, ku = 3.5. Case 3 refers to the performance of analyzing severely skewed and heavy-tailed data with sk = 0.5, ku = 4.0. (a) The performance of segmentation using the hybrid CBS and eCBS with large signal-to-noise ratios (SNR) (c = 2), and (b) with small SNR (c = 1.5).Back to article page