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Figure 5 | BMC Research Notes

Figure 5

From: A model-based circular binary segmentation algorithm for the analysis of array CGH data

Figure 5

The comparison of ROC curves between the hybrid CBS and eCBS. The ROC curves obtained from the segmentation results of 10,000 simulated datasets. Each dataset contained 1,500 probes. Case 1 refers to the performance of analyzing normally distributed data with sk = 0, ku = 3. Case 2 refers to the performance of analyzing mildly skewed and heavy-tailed data with sk = 0.2, ku = 3.5. Case 3 refers to the performance of analyzing severely skewed and heavy-tailed data with sk = 0.5, ku = 4.0. (a) The performance of segmentation using the hybrid CBS and eCBS with large signal-to-noise ratios (SNR) (c = 2), and (b) with small SNR (c = 1.5).

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