From: Detection of primary sites in unknown primary tumors using FDG-PET or FDG-PET/CT
Patient no. | Sex | Age | Site of metastases | Pathology | PET or PET/CT | PET or PET/CT finding | Primary site detected by IHC | IHC markers used to detect primary site | |||
---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  |  |  |  | Primary tumor | Known metastases | Additional findings | Results of additional findings |  |  |
1 | M | 54 | Cervical LN | Squamous cell ca. | PET | not seen | seen | - | - | - | - |
2 | F | 66 | Bone | PD | PET/CT | not seen | seen | - | - | - | Vimentin, CK 7, CK 20, CD 68 |
3 | M | 55 | Cervical LN | PD | PET→PET/CT | not seen | seen | - | - | - | CK 7, CK 19, CK 20, Thyroglobulin, |
4 | F | 57 | Bone | Signet ring cell ca. | PET/CT | not seen | seen | Neck, thyroid, hand, forearm uptake | Benign | - | CK 7, CK 20, TTF-1, ER, PR |
5 | M | 56 | Skin | Adenocarcinoma | PET→PET/CT | not seen | not seen | Mid-esophagus uptake (subcarinal LN) | Benign | - | CK 7, CK 19, CK 20 TTF-1 |
6 | F | 36 | Bone | Adenocarcinoma | PET | not seen | seen | - | - | Breast | ER, PR, C-erbB2, CK 7, CK 20, TTF-1, GCDFP-15 |
7 | F | 62 | Abdominal LN | PD | PET/CT | not seen | seen | Pharynx, thyroid, uptake | Benign | - | - |
8 | M | 15 | Cervical LN | PD | PET | not seen | seen | - | - | - | CK, Vimentin, CD 68 |
9 | M | 54 | Cervical LN | Squamous cell ca. | PET/CT | not seen | seen | - | - | - | - |
10 | M | 46 | Brain | Leiomyosarcoma | PET→PET/CT | not seen | seen | Left lower lung uptake | Benign | - | CD 34, Smooth muscle actin, CD 68 |
11 | F | 34 | Cervical LN | PD | PET | not seen | seen | - | - | Lung | CK 7, CK 20, TTF-1 |
12 | F | 60 | Omentum | Adenocarcinoma | PET/CT | not seen | * | * | * | - | CK7, CK 20 |
13 | F | 48 | Peritoneum | Adenocarcinoma | PET/CT | not seen | seen | Inguinal LN uptake | Malignant | - | CK7, CK 20 |
14 | F | 60 | Axillary LN | PD | PET | not seen | seen | - | - | - | CK 7, CK 20, TTF-1 |
15 | M | 61 | Cervical LN | PD | PET→PET/CT | not seen | seen | - | - | - | CK, leukocyte common antigen |
16 | F | 53 | Ureter | PD | PET/CT | not seen | * | * | * | - | CK 7, CK 20 |
17 | M | 59 | Abdominal LN | Adenocarcinoma | PET/CT | not seen | seen | Thyroid uptake | Benign | - | CK 7, CK 19, CK 20, TTF-1 |
18 | M | 68 | Abdominal LN | PD | PET | not seen | * | * | * | - | CD 56, CK |
19 | F | 51 | Axillary LN | PD | PET/CT | not seen | seen | - | - | - | CK 7, CK 20, TTF-1 |
20 | F | 43 | Bone | PD | PET | not seen | seen | Neck LN uptake | Malignant | - | CK 7, CK 20 |