Figure 1From: Ribozyme-mediated gene knock down strategy to dissect the consequences of PDGF stimulation in vascular smooth muscle cellsKinetic characterization and ribozyme transfection. A) Graph describing the Eadie-Hofstee interpolation of experimental kobs values (v0/[Riboz]) calculated for the in vitro cleavage of synthetic substrate under multiple turnover conditions. The resulting kinetic parameters are also indicated. B) fluorescence microscopy image of VSMCs after OligoF administration. The intracellular fluorescence demonstrates the oligonucleotide internalizationBack to article page