Table 5 Cytokine and immune mediator concentrations in amniotic fluid by maternal age
Mediator | Age | Age | Age | Age | Age | p-value |
|---|---|---|---|---|---|---|
19-25 | 26-30 | 31-35 | 36-40 | >40 | ||
IL-2 (n = 66) | 5.2 | 4.6 | 4.3 | 3.8 | 3.9 | 0.97 |
IL-4 (n = 182) | 8.3 | 6.6 | 9.0 | 9.2 | 9.7 | 0.18 |
IL-6 (n = 156) | 879.2 | 668.9 | 738.7 | 669.2 | 832.8 | 0.97 |
IL-8 (n = 185) | 829.5 | 551.4 | 754 | 621.0 | 552.1 | 0.45 |
IL-10 (n = 161) | 9.1 | 7.1 | 5.8 | 5.5 | 5.1 | 0.49 |
IL-12 (n = 161) | 5.1 | 5.8 | 4.9 | 5.3 | 5.5 | 0.94 |
IL-15 (n = 173) | 35.8 | 31.3 | 28.0 | 12.3 | 11.5 | 0.51 |
IL-17 (n = 66) | 32.7 | 19.3 | 19.2 | 23.4 | 21.8 | 0.46 |
TNF- α (n = 161) | 9.3 | 11.0 | 12.1 | 13.0 | 12.1 | 0.56 |
GRO- α (n = 184) | 629.5 | 1254.3 | 1228.1 | 663.0 | 492.9 | 0.01 |
Pro IL1-ß (n = 157) | 19.8 | 19.5 | 16.9 | 19.4 | 17.0 | 0.48 |
Histone (n = 161) | 0.3 | 0.2 | 0.3 | 0.3 | 0.3 | 0.83 |
IP-10 (n = 169) | 1435.3 | 644.6 | 722.7 | 814.0 | 702.8 | 0.33 |
MIP1-ß (n = 182) | 27.5 | 25.8 | 28.3 | 25.9 | 27.7 | 0.71 |
MIP1- α (n = 186) | 25.6 | 25.9 | 25.7 | 24.8 | 26.0 | 0.79 |