Table 2 Summary of maximum likelihood estimates of penetrance parameters
From: MLEP: an R package for exploring the maximum likelihood estimates of penetrance parameters
True value | 0.0001 | |||||
|---|---|---|---|---|---|---|
Assumed value | 0.0001 | 0.001 | 0.01 | 0.1 | 0.25 | 0.5 |
MLE | (0.832,0.759,0.003) | (0.766,0.757,0.002) | (0.749,0.749,0.001) | (0.690,0.688,0.000) | (0.989,0.159,0.000) | (0.602,0.002,0.000) |
Bias | (0.118,0.112,0.002) | (0.124,0.112,0.002) | (0.145,0.110,0.002) | (0.188,0.143,0.001) | (0.204,0.379,0.001) | (0.330,0.628,0.001) |
MSE | (0.020,0.020,0.000) | (0.023,0.020,0.000) | (0.035,0.020,0.000) | (0.064,0.030,0.000) | (0.082,0.183,0.000) | (0.142,0.415,0.000) |
True value | 0.001 | |||||
Assumed value | 0.0001 | 0.001 | 0.01 | 0.1 | 0.25 | 0.5 |
MLE | (0.832,0.759,0.003) | (0.766,0.757,0.002) | (0.749,0.748,0.001) | (0.617,0.614,0.000) | (0.916,0.208,0.000) | (0.592,0.003,0.000) |
Bias | (0.118,0.112,0.002) | (0.124,0.112,0.002) | (0.145,0.111,0.002) | (0.215,0.135,0.001) | (0.213,0.380,0.001) | (0.360,0.656,0.000) |
MSE | (0.020,0.020,0.000) | (0.023,0.020,0.000) | (0.035,0.020,0.000) | (0.076,0.026,0.000) | (0.085,0.180,0.000) | (0.149,0.441,0.000) |
True value | 0.01 | |||||
Assumed value | 0.0001 | 0.001 | 0.01 | 0.1 | 0.25 | 0.5 |
MLE | (0.772,0.767,0.010) | (0.766,0.765,0.008) | (0.753,0.753,0.002) | (0.632,0.612,0.000) | (0.880,0.279,0.000) | (0.586,0.000,0.000) |
Bias | (0.111,0.110,0.003) | (0.114,0.110,0.003) | (0.132,0.109,0.003) | (0.191,0.127,0.001) | (0.197,0.365,0.001) | (0.356,0.648,0.000) |
MSE | (0.017,0.020,0.000) | (0.019,0.020,0.000) | (0.031,0.019,0.000) | (0.063,0.024,0.000) | (0.075,0.170,0.000) | (0.145,0.430,0.000) |
True value | 0.01 | |||||
Assumed value | 0.0001 | 0.001 | 0.01 | 0.1 | 0.25 | 0.5 |
MLE | (0.972,0.802,0.010) | (0.962,0.804,0.010) | (0.925,0.799,0.010) | (0.776,0.680,0.000) | (0.764,0.440,0.000) | (0.591,0.017,0.000) |
Bias | (0.083,0.116,0.007) | (0.095,0.118,0.007) | (0.106,0.116,0.006) | (0.125,0.111,0.002) | (0.181,0.269,0.002) | (0.272,0.588,0.001) |
MSE | (0.011,0.020,0.000) | (0.013,0.021,0.000) | (0.018,0.021,0.000) | (0.033,0.020,0.000) | (0.056,0.102,0.000) | (0.099,0.373,0.000) |
True value | 0.2 | |||||
Assumed value | 0.0001 | 0.001 | 0.01 | 0.1 | 0.25 | 0.5 |
MLE | (0.995,0.765,0.010) | (0.998,0.777,0.010) | (0.964,0.778,0.010) | (0.697,0.647,0.005) | (0.719,0.381,0.000) | (0.631,0.074,0.000) |
Bias | (0.104,0.129,0.009) | (0.104,0.130,0.009) | (0.108,0.139,0.008) | (0.142,0.132,0.005) | (0.203,0.220,0.003) | (0.308,0.579,0.002) |
MSE | (0.018,0.026,0.000) | (0.019,0.026,0.000) | (0.023,0.028,0.000) | (0.043,0.030,0.000) | (0.070,0.071,0.000) | (0.124,0.351,0.000) |