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Figure 1 | BMC Research Notes

Figure 1

From: Specific-mutational patterns of p53 gene in bladder transitional cell carcinoma among a group of Iraqi patients exposed to war environmental hazards

Figure 1

Example of PCR-SSCP/HD and DNA sequencing analysis of p53 gene in transitional cell carcinoma. (a) PCR-SSCP/HD analysis of exon 5 shows extra bands and bands with mobility shift indicated by arrows (−ve: undenaturated DNA control; +ve: denaturated DNA control, and T: tumors). DNA sequencing reveals transition CGC → CAC at codon 175 in exon 5 (b) and insertion A after codon 244 (GGC) in exon in exon 7 (d) in compared to wild types (c) and (e) respectively (arrows).

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