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Table 3 Mouse experiment fold-changes

From: MetabR: an R script for linear model analysis of quantitative metabolomic data

 

Treatment comparison

 

BPA500-BPA50

BPA5000-BPA50

Control-BPA50

BPA5000-BPA500

Control-BPA500

Control-BPA5000

Metabolite

Fold-change

P-value

Fold-change

P-value

Fold-change

P-value

Fold-change

P-value

Fold-change

P-value

Fold-change

P-value

Bisphenol A

0.817

0.998

0.455

0.423

1.420

0.984

0.558

0.490

1.738

0.946

3.117

0.261

Glucose-6-phosphate

1.042

0.081

0.987

0.859

1.023

0.545

0.947

0.013

0.981

0.654

1.036

0.168

Lactate

1.663

0.298

1.177

0.923

1.353

0.401

0.708

0.652

0.814

0.997

1.149

0.771

Citrate

1.064

1.000

3.265

0.120

2.273

0.219

3.070

0.141

2.137

0.252

0.696

0.988

Isocitrate

0.809

0.219

1.134

0.644

1.117

0.731

1.401

0.019

1.380

0.026

0.985

0.999

Phosphoenolpyruvate

1.218

0.551

1.476

0.167

0.793

0.962

1.212

0.852

0.651

0.287

0.537

0.064

Thymine

0.868

0.919

0.552

0.025

1.118

0.972

0.636

0.100

1.288

0.710

2.026

0.009

Urea

1.325

0.971

0.960

0.993

1.084

0.947

0.725

0.894

0.818

1.000

1.129

0.849

N-Acetyl-L-glutamate

0.449

0.001

0.518

0.007

0.548

0.014

1.152

0.789

1.220

0.638

1.059

0.994

ADP

1.264

0.907

7.812

0.092

11.948

0.035

6.180

0.280

9.452

0.124

1.530

0.957

Tryptophan

1.086

0.998

0.757

0.461

0.870

0.912

0.697

0.367

0.801

0.841

1.150

0.843

Ornithine

1.813

0.008

1.563

0.071

1.231

0.476

0.862

0.776

0.679

0.189

0.788

0.686

  1. Mean fold-changes among the four treatment groups for the mouse example data (12 metabolites across positive and negative ionization modes), and associated Tukey HSD p-values for mean differences (bold values are p < 0.05).