Skip to main content

Table 1 Summary of checkerboard results: 26 H. pylori strains tested with clarithromycin versus amoxicillin correlated to mutations in 23S rRNA

From: Influence of a 23S ribosomal RNA mutation in Helicobacter pylori strains on the in vitro synergistic effect of clarithromycin and amoxicillin

Mutation in 23S rRNA gene

No. of strains

Synergy (FIC < 0.5)

MIC

A2143G

10

5 (50%)

<2

A2142G

12

3 (25%)

>16

  1. FIC: fractional inhibitory concentration[8].