Figure 5

Two true differentially expressed GO terms identified by either GSEA + MIMGO or GSEA (Pearson). A, expression of genes annotated to “DNA synthesis involved in DNA repair”. This is a true differentially expressed GO term that GSEA + MIMGO, but not GSEA (Pearson), was able to identify in the first set (“7 GO terms upregulated at 14 min, 21 min, 70 min, and 77 min”) of Table 3. The vertical axis shows the expression of genes (YKL113C, YNL102W, YKL045W, and YNL262W) annotated with “DNA synthesis involved in DNA repair” in the microarray data. B, expression of genes annotated with “Replication fork protection”. “Replication fork protection” is a true differentially expressed GO term that GSEA (Pearson), but not GSEA + MIMGO, was able to identify in the first set (“7 GO terms upregulated at 14 min, 21 min, 70 min, and 77 min”) of Table 3. The vertical axis shows the expression of genes (YBR274W, YDL101C, YAL021C, YNL273W, and YCL061C) annotated with “Replication fork protection” in the microarray data.