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Table 3 Comparison of GSEA + MIMGO and GSEA (Pearson) for the identification of three sets of true differentially expressed GO terms

From: Validation of MIMGO: a method to identify differentially expressed GO terms in a microarray dataset

 

7 GO terms upregulated at 14min, 21min, 70min, 77min

22 GO terms upregulated at 7min, 14min, 21min

5 GO terms upregulated at 0min

GSEA + MIMGO

2 / 7 (28%)

7 / 22 (31%)

1 / 5 (20%)

GSEA (Pearson)

2 / 7 (28%)

11 / 22 (50%)

1 / 5 (20%)

GO terms identified in both methods

1

6

1

  1. The sets of GO terms are described in detail in the text. “GSEA + MIMGO” and “GSEA (Pearson)” denote proportion of true differentially expressed GO terms that were detected by GSEA + MIMGO and GSEA (Pearson) for each set of true differentially expressed GO terms, respectively. ”GO terms identified in both methods" shows the number of the true differentially expressed GO terms identified in both GSEA + MIMGO and GSEA (Pearson).