Figure 2
Sirius Red staining of hepatic structure in vehicle rats (A) compared to CCl 4 treated rats (B) after 8 weeks of treatment. The hepatic tissue architecture around the portal tracts is disrupted in fibrotic livers compared to vehicle and the amount of collagen is increased. Immunohistochemical analysis of α-SMA in vehicle rats ( C ) and CCl4 treated rats (D). α-SMA is localized around the fibrotic bands. Original magnification ×40.