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Figure 7 | BMC Research Notes

Figure 7

From: Evolution of the eukaryotic ARP2/3 activators of the WASP family: WASP, WAVE, WASH, and WHAMM, and the proposed new family members WAWH and WAML

Figure 7

Domain organisation of representative WHAMM proteins. A colour key to the domain names and symbols is given on the right except for the WMD domain and the poly-proline region (PPR) that are coloured in dark green and yellow, respectively. The class-2 and class-3 WHAMM homologs encode insertions in the WMD domain. For Hs WHAMM2 the insertion is symbolized by light-green bars. The sequence logo illustrates the sequence conservation within the multiple sequence alignments of the previously supposed third WH2 domain in class-2 WHAMM homologs. However, the sequence is not in accordance with the consensus WH2 sequence motif. Species abbreviation: Hs = Homo sapiens.

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