Table 1 Clinical characteristics of the Amish*
From: Polymorphisms in the SOCS7 gene and glucose homeostasis traits
Trait | T2DM | NGT | NGT + IGT |
|---|---|---|---|
(n = 145) | (n = 358) | (n = 765) | |
% female | 69.7 | 48.0 | 52.6 |
Age (yrs) | 65 ± 12 | 51 ± 11 | 44.3 ± 14.7 |
BMI (kg/m2) | 30.1 ± 4.0 | 27.4 ± 4.7 | 27.0 ± 4.8 |
% IGT | - | - | 19.1 |
Age of onset of DM (yrs) | 59 ± 11 | - | - |
HOMA-IR | - | 2.5 ± 1.5 | 2.5 ± 1.4 |
Fasting Glucose (mmol/L) | - | 5.04 ± 0.42 | 5.02 ± 0.46 |
2 hour Glucose (mmol/L) | - | 5.76 ± 1.20 | 6.21 ± 1.7 |
Fasting Insulin† (pmol/L) | - | 68.1 (55.6, 86.8) | 66.7 (54.9, 86.1) |
2 hour Insulin† (pmol/L) | - | 211.8 (126.4, 341.0) | 218.8 (128.5, 364.6) |
AUC Glucose (mmol/L) | - | 349.2 ± 51.5 | 359.9 ± 67.2 |
AUC Insulin† (pmol/L) | - | 761.9 (540.3, 1046.6) | 752.1 (525.0, 1046.6) |