Table 1 Baseline clinical characteristics by different outcomes and treatment groups

48 (28–71)

49 (28–71)

36.5 (29–51)

0.226

48 (29–65)

47 (28–71)

0.859

1.000

1.000

18

14

4

8

10

3

3

0

1

2

9/12

7/10

2/2

1.000

−

−

−

−

−

−

−

2

2

1.000

9

7

2

1.000

3

6

0.660

3

2

1

0.489

1

2

1.000

3

1

2

0.080

1

2

1.000

1

1

0

0.190

1

0

0.429

19.4 (0.8–28.2)

25.0 (4.0–28.2)

1.45 (0.8–2.5)

0.002

5.1 (1.9–28.2)

24.7 (0.8–27.7)

0.722

3.49 (2.5–4.9)

3.6 (2.5–4.9)

2.95 (2.5–3.3)

0.020

3.6 (2.9–4.2)

3.4 (2.5–4.9)

0.477

1270 (146–2480)

1270 (211–2480)

1197 (146–2247)

0.929

1523 (211–2480)

870 (146–2247)

0.177

9.2 (2.1–33.1)

7.7 (2.1–16.8)

20.6 (11.9–33.1)

0.007

8.6 (2.1–20.4)

10.25 (2.2–33.1)

0.356

0.68 (0.39–1.46)

0.71 (0.47–1.34)

0.48 (0.39–1.46)

0.165

0.71 (0.47–1.05)

0.63 (0.39–1.46)

0.972

116 (53–254)

116 (53–183)

194.5 (54–254)

0.106

116 (73–201)

127 (53–254)

0.831

111.1 (52.9–156.7)

110.1 (52.9–131.1)

138.2 (59.8–156.7)

0.152

112 (77.8–148)

110.6 (52.9–156.7)

0.722

148 (44–253)

148 (62–253)

121.5 (44–174)

0.244

174 (44–251)

121.5 (62–253)

0.188

1.6 (1.3–3.5)

1.5 (1.3–2.3)

3.3 (2.6–3.5)

0.002

1.5 (1.3–3.1)

1.6 (1.4–3.5)

0.773

65.7 (4.1–650.7)

49.4 (4.1–477.2)

109.5 (27.9–650.7)

0.325

27.9 (4.2–238.3)

162.1 (4.1–650.7)

0.088

8.04 (4.3–9.68)

8.16 (5.22–9.68)

5.06 (4.30–8.20)

0.031

8.04 (4.97–9.47)

8.04 (4.30–9.68)

0.886

20 (13–37)

19 (13–28)

31.5 (26–37)

0.003

19 (14–31)

20 (13–37)

0.412