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Table 1 Adrenal insufficiency after orthopaedic surgery

From: Acute adrenal insufficiency following arthroplasty: a case report and review of the literature

Cases

Author

Country

Age

Sex

Type of surgery

Diagnosis

Symptoms

Biochemical exams

1

Findling et al., 1987 [15]

USA

44

M

unspecified

CT

abdominal pain, vomiting, hypotension

hyponatremia, hyperkalemia

2

Delhumeau et al., 1989 [16]

France

76

F

total hip arthroplasty

abdominal ultrasound

abdominal pain, fever, hypotension, altered consciousness

hyponatremia, natriuresis, thrombocytopenia

3

74

M

tibial osteosynthesis

not done

abdominal pain, fever, hypotension, shock, altered consciousness

hyponatremia, thrombocytopenia

4

62

M

tibial osteosynthesis

CT

abdominal pain, asthenia, nausea

hyponatremia, thrombocytopenia

5

Ernest and Fischer, 1991 [17]

Australia

68

F

total hip arthroplasty

CT

fever, hypotension

hyponatremia, hyperkalemia

6

Souied et al., 1991 [18]

France

63

F

total hip arthroplasty

CT

fever, hypotension

hyponatremia, hyperkalemia

7

Bleasel et al., 1992 [19]

Australia

69

F

total knee arthroplasty

CT

fever, nausea, vomiting, abdominal pain, hypotension

hyponatremia, hyperkalemia

8

Hardwicke and Kisly, 1992 [20]

USA

63

F

bilateral total knee arthroplasty

CT

fever, nausea, anorexia, vomiting, abdominal pain, confusion, feeling of illness, hypotension

anemia, hyponatremia, hyperkalemia

9

Delhumeau et al., 1993 [21]

France

74

M

total hip arthroplasty, thrombectomy of both limbs due to bilateral arterial thrombosis

CT

abdominal pain, fever, hypotension, abdominal tenderness

hyponatremia, hyperkalemia

10

Santonastaso et al., 1993 [22]

Italy

not reported

F

osteotomy

CT

somnolence, asthenia, hypotension

not reported

11

Ries et al., 1994 [23]

USA

61

F

bilateral total knee arthroplasty

autopsy

abdominal discomfort, nausea, collapse

none

12

Cozzolino et al., 1997 [24]

USA

66

F

total knee arthroplasty

CT

nausea, anorexia, emesis, lethargy

hyponatremia, hyperkalemia, anemia, azotemia

13

Rowland et al., 1999 [25]

Australia

50

M

unspecified

CT

fever, abdominal pain, dizziness, hypotension

hyponatremia

14

Caubet et al., 1999 [26]

France

63

F

tibial osteosynthesis

CT

fever, hypotension, tachypnea

thrombocytopenia, hyponatremia, hyperkalemia, elevated INR

15

Scheffold et al., 2001 [27]

Germany

63

M

intracondylar nail-extension

abdominal ultrasound

abdominal pain, fever

leukocytosis

16

LaBan et al., 2003 [28]

USA

82

F

bilateral knee arthroplasty

CT

abdominal pain, nausea

elevated INR, hyponatremia

17

Schuchmann et al., 2005 [8]

USA

83

F

bilateral total knee arthroplasty

autopsy

anxiety, hypertension, midback pain, shortness of breath, shock

hyponatremia, hypochloremia, leukocytosis, anemia, elevated INR

18

Kurtz and Yang, 2007 [29]

USA

54

F

total hip arthroplasty

CT

fever, abdominal pain, orthostatic syncope

not reported

19

Mongardon et al., 2007 [30]

France

64

M

total hip arthroplasty

CT

fever, abdominal pain, confusion, hypotension

thrombocytopenia, high urinary sodium

20

Thota et al., 2012 [31]

USA

68

M

bilateral total knee arthroplasty

CT

fever, abdominal discomfort, anorexia, fatigue, hypertension, tachycardia, altered mental status

hyperglycemia, leukocytosis, anemia, thrombocytopenia, hyponatremia

21

Chow et al., 2012 [32]

USA

44

M

bilateral total knee arthroplasty

CT

hypotension, abdominal pain, tachycardia, fever

leukocytosis, D-dimers elevation, hyponatremia, thrombocytopenia