Spontaneous closure of a macular hole (MH) in the left eye of a 71-year-old man with an idiopathic full-thickness macular hole and subclinical posterior vitreous detachment. a: Initial examination. Spectral-domain optical coherence tomographic (SD-OCT) scan passing through the fovea horizontally showing a full-thickness MH. The diameter of the MH at the level of the retinal pigment epithelium was 396 μm. A membranous tissue (arrowhead), probably the internal limiting membrane and/or part of the vitreous cortex is seen adhered to the retinal surface at the MH margin. Neither a pseudo-operculum nor intraretinal cysts is seen. b: Three weeks later, SD-OCT showed tissue (p) protruding from the interior wall of the MH. The tissue extends from the end of the elevated and disrupted external limiting membrane (ELM) toward the opposite side of the MH. c: SD-OCT at 5 months after the initial visit showing a MH closed by thin retinal tissue that extends from the outer portion of the outer nuclear layer (ONL) including the ELM across the MH. An inner segment/outer segment (IS/OS) junction defect and foveal detachment are present. d: Seven months after the initial visit, the IS/OS junction defect had essentially recovered. The foveal detachment had recovered.