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Figure 5 | BMC Research Notes

Figure 5

From: Vectorial secretion of interleukin-8 mediates autocrine signalling in intestinal epithelial cells via apically located CXCR1

Figure 5

Network showing linked GO categories representing the functional annotation of the genes that were differentially transcribed in Caco-2 BBE cells after stimulation with IL-8. Gene ontology (GO) terms make up a formal vocabulary to describe gene functions. This network illustrates the biological processes corresponding to the transcriptome changes. Note that these GO categories exemplify cell migration, signalling and differentiation and therefore correlate well with the core protein-protein interaction network depicted in FigureĀ 4 (see text for details). MAPK, MAP kinase; PLC, phospholipase C; GPCR, G protein-coupled receptor; IP3, inositol 1,4,5-trisphosphate.

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