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Figure 4 | BMC Research Notes

Figure 4

From: Development of plasma cell myeloma in a B-cell chronic lymphocytic leukemia patient with chromosome 12 trisomy

Figure 4

Identification of chromosome 12 trisomy in B-CLL cells, but not in myeloma cells by FISH. Dual color FISH for the genes ETV6 and RUNX1, whose probes detect the chromosome 12 (green) and chromosome 21 (red) respectively. A and B: Myeloma plasma cells presented two copies of each chromosome, thus negative for the trisomy. C and D: Nucleus carrying chromosome 12 trisomy were detected in 91% the cells in the CD138(−) fraction.

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BMC Research Notes

ISSN: 1756-0500

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