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Table 2 Analyses of Lineweaver–Burk plots for BCRP

From: Biochemical interaction of anti-HCV telaprevir with the ABC transporters P-glycoprotein and breast cancer resistance protein

 

Vmax(pmol/mg/10 min)

Ki(μmol/L)

No inhibitor

With 50 μmol/L telaprevir

E1S

37.5

41.2

44.4

MTX

4.9

4.6

94.8