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Table 1 Overview of the parameters for 3N and 4N

From: Inferring protein–protein interaction complexes from immunoprecipitation data

 

External for 3N

External for 4N

Affects totalnumber ofproteins incomplexes

Description

L

Yes

 

Yes

Length of topList

T

Yes

 

Yes

Co-occurrence thresholdinfluencing param.

C

Yes

Yes

Yes

Cosinus-distance threshold

S

Yes

No

Yes

Jaccard coefficient threshold for building CCs

U

 

No

Yes

Jacc. coeff. threshold forbuilding NNNs

P

 

Yes

No

Jaccard coefficient threshold for joining CCs

  1. External parameters are those that need to be adjusted by the user. The non-external parameters of 4N are set automatically by the algorithm.