Figure 1

Location of potential phosphorylation sites in the NOD1 CARD. Potential serine, threonine and tyrosine phosphorylation sites in the first 120 residues of NOD1 were identified using NETPhos 2.0. (A) Location of potential phosphorylation sites in the primary sequence of the first 120 residues of NOD1. Black boxes denote the location of helices in the CARD. (B) Potential phosphorylation residues are shown as ball representations on the tertiary structure of the NOD1 CARD [PDB: 2dbd]. The left and right images are related by a 180° rotation around the vertical axis. Colouring in (A) and (B) is as follows: green – serine, pink – threonine, yellow - tyrosine.