Table 3 Univariate and multivariate analysis for parental factors associated with congenital anomalies among young infants admitted at Bugando Medical Centre
Parental risk factor | Congenital malformations | Unadjusted | Adjusted | |||
|---|---|---|---|---|---|---|
Yes | No | OR [95% CI] | P-value | OR [95% CI] | P-value | |
Maternal age | ||||||
≤35 | 112 (27.6) | 293 (72.4) | 1 | 1 | ||
>35 | 19 (47.5) | 21 (52.5) | 2.4 [1.2-4.6] | 0.010 | 2.2 [1.1-4.3] | 0.024 |
Antenatal visit | ||||||
>3 visit | 51 (21.3) | 188 (78.7) | 1 | 1 | ||
≤3 visit | 79 (38.9) | 124 (61.1) | 2.3 [1.5-3.6] | <0.001 | 2.1 [1.4-3.3] | <0.001 |
Passive smoking | ||||||
No | 115 (29.3) | 277 (70.7) | 1 | |||
Yes | 15 (30) | 35 (70) | 1.03 [0.5-2] | 0.923 | _ | _ |
Maternal alcohol intake | ||||||
No | 129 (30) | 301 (70) | 1 | |||
Yes | 1 (8.3) | 11 (91.7) | 0.21 [0.3-1.7] | 0.140 | _ | _ |
Maternal use of folic acid | ||||||
Yes | 8 (11.9) | 59 (88.11) | 1 | 1 | ||
No | 122 (32.5) | 253 (67.5) | 3.6 [1.6-7.7] | 0.001 | 3.1 [1.4-6.7] | 0.005 |
Paternal age | ||||||
<45 | 117 (28.5) | 293 (71.5) | 1 | |||
≥45 | 13 (40.6) | 19 (59.4) | 1.7 [0.8-3.6] | 0.152 | _ | _ |