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Table 1 Univariate comparison between PCP positive and negative patients by presenting clinical and laboratory data

From: Pneumocystis pneumonia in South African children diagnosed by molecular methods

Variable

PCP positive

PCP negative

p

 

n = 109

n =93

 

Presenting symptoms n (%)

Cough

94 (86.2)

78 (83.9)

0.6

Fever

30 (27.5)

47 (50.5)

0.0008

Poor feeding

28 (25.7)

21 (22.6)

0.6

Patient characteristics

Gender M:F

47:62

45:48

0.5

Age (Months)

3.4 (2.7 – 4.0)

2.2 (1.3 – 6.8)

0.03

HIV infected n (%)

87 (79.8)

37 (39.8)

<0.0001

HIV exposed, uninfected

5 (4.6)

29 (31.2)

<0.0001

Weight for age Z score

−2.9 (−4.6 - -1.6)

−2.4 (−3.9 - -1.36)

0.08

Height for age Z score

−2.4 (−4.5 - -0.9)

−2.3 (−3.2 - -0.9)

0.24

Duration of symptoms (days )

3.0 (2.0 – 7.0)

3.0 (1.0 – 7.0)

0.66

Admission signs

Respiratory rate on admission (breaths per minute)

70.0 (60.0 – 80.0)

60.0 (50 – 70)

0.0002

Subcostal recessions n (%)

107 (98.2)

83 (89.2)

0.8

SpO2 (%) in room air (n = 146)

77.0 (65.5 – 84.0)

87.5 (75.0 – 92.0)

<0.0001

Laboratory investigations

CD4% in HIV infected children

17.1 (9.9 – 29.7)

21.0 (14.7 – 29.7)

0.12

n = 80

n = 35

Lactate dehydrogenase (u/l)

710.5 (534.5 – 1067.0)

350.0 (238.0 – 610.0)

<0.0001

 

n = 57

n = 35

 
  1. Continuous data are median (interquartile range).