Figure 5

Multiple sequence alignment of BIG3 and its homologues near the putative PHB2-binding site. Multiple sequence alignment of the N-terminal portions (region A in Figure 1) of BIG3 and its homologues was generated by MAFFT (see Additional file 2 for the full alignment). The red box corresponds to the residues in the red background in Figure 3. The verified PHB2-binding residues are indicated with black triangles.