Figure 2

Distribution of the RNA MTase sequence motifs across bacterial genomes. Using the amino acid profiles inferred from the probabilistic methods, a search for the proteins matching the RNA MTase sequences was done. Information on query and alignment length, and on the score for amino acid replacements was used to draw the density violin plots per family and class of RNA MTases. Orthology was considered for those hits (with few exceptions) with a Similarity Index higher than 7.5, whereas paralogy was considered for hits with a Similarity Index 5.0 to 7.5. *Refers to the N-terminal domain of the bi-functional MnmC enzyme.