Figure 2
Inspired and end-expired sevoflurane concentrations during wash-in (a) and maintenance (b) (upper and lower line, thick line = mean, thin lines = standard deviation), and corresponding liquid sevoflurane injection rate (mL/h) (c and d, respectively). During the first 5 minutes (c), the liquid sevoflurane injection rate (mL/h) could not be accurately measured between 15 ± 2 and 46 ± 6 sec because Vinjsevo was > 100 mL/h (see text for details). The sevoflurane injection rates match those of previously published sevoflurane uptake data derived from several different sources (d): closed circuit liquid injection (yellow line = Lockwood data, green line = Hendrickx data) [3, 4], indirect calorimetry (gas balances within the circuit = red line) [5, 6], and the reverse Fick method (pink line) [5, 6]. Thick lines = median, thin lines = quartiles.