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Table 1 FISH mapping of 1p21-22 amplicon

From: Mapping of the chromosomal amplification 1p21-22 in bladder cancer

Clones

Chromosome location

Cell lines

   
  

SCaBER

HT-1376

UM-UC-3

TCCSUP

RT4

J82

T24

5637

RP11-82E1

91,116,728–91,294,152

3/4 (0.9)

      

3/3 (1.00)

RP5-865 M20

92,068,692–92,181,253

2/4 (0.54)

10/6 (1,53)

 

3/4 (0.86)

4/4 (0.98)

3/3 (1.00)

3/3 (1.17)

3/3 (1.00)

RP4-621B10

92,517,154–92,659,879

2/4 (0.54)

10/6 (1.89)

 

3/4 (0.86)

4/4 (1.00)

3/3 (1.00)

3/3 (1.12)

3/3 (1.00)

RP5-1014C4

92,854,755–93,007,879

7/4 (2.02)

11/6 (1.91)

4/4 (1.02)

    

3/3 (1.00)

RP11-977E2

93,042,494–93,249,510

8/4 (2.35)

10/6 (1.65)

3/4 (0.75)

3/4 (0.73)

4/4 (0.93)

3/3 (0.86)

4/3 (1.24)

3/3 (1.00)

RP5-976O13

93,529,940–93,632,330

10/4 (3.07)

10/6 (1.64)

 

3/4 (0.78)

 

3/3 (1.06)

 

3/3 (1.00)

RP4-713B5

93,760,493–93,865,044

11/4 (3.02)

10/6 (1.83)

     

3/3 (1.00)

RP11-272P3

94,980,681–95,180,686

3/4 (0.99)

11/6 (1.91)

     

3/3 (1.00)

RP11-146P11

95,983,612–96,156,674

4/4 (1.04)

10/6 (1.85)

4/4 (1.05)

3/4 (0.82)

4/4 (1.05)

3/3 (0.93)

 

3/3 (1.00)

RP11-122C9

97,095,507–97,282,884

3/4 (1.07)

10/6 (1.91)

     

3/3 (1.00)

  1. The first value represents the median of signals from the locus-specific probe indicated under ‘clones’; the second value represents the median number of signal from the chromosome 1 centromeric probe. The ratio between the two values is bracketed. SCaBER cell line shows a high level amplification between the positions 92,854,755 and 93,865,044 (GRCh37/h19), whereas HT-1376 cell line shows a copy-number gain.
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BMC Research Notes

ISSN: 1756-0500

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