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Table 2 Comparison of the frequency distributions of rs779805 and rs1642742 of VHL gene in the germline DNA of RCC patients with normal controls

From: Two single nucleotide polymorphisms in the von Hippel-Lindau tumor suppressor gene in Taiwanese with renal cell carcinoma

 

rs779805

rs1642742

 
 

19 RCCs#

616 controls#

19 RCCs#

616 controls#

Genotype distribution

    

 AA

12 (63.16%)

470 (76.30%)

11 (57.89%)

467 (75.81%)

 AG

7 (36.84%)

132 (21.43%)

8 (42.10%)

134 (21.75%)

 GG

0

14 (2.27%)

0

15 (2.44%)

Allele frequency

    

 A allele

31 (81.58%)

1072 (87.01%)

30 (78.95%)

1068 (86.69%)

 G allele

7 (18.42%)

160 (12.99%)

8 (21.05%)

164 (13.31%)

Homozygous genotype

    

 (AA or GG genotype)

12 (63.16%)

484 (78.57%)

11 (57.89%)

482 (78.25%)

Heterozygous genotype

    

 (AG genotype)

7 (36.84%)

132 (21.43%)

8 (42.01%)

134 (21.75%)

Allele carriage frequency

    

 A allele (AA+AG)

19 (100%)

602 (97.73%)

19 (100%)

601 (97.56%)

 G allele (AG+GG)

7 (36.84%)

146 (23.70%)

8 (42.10%)

149 (24.19%)

  1. #Data presented as number of cases and percentage; bold text means statistical significance was reached, p < 0.05, in the comparison of germline DNA between RCC patients and controls.