From: Independent effects of sham laparotomy and anesthesia on hepatic microRNA expression in rats
# | miRNA | Strongest expression change | Putative targets | |
---|---|---|---|---|
A. miRNAs similarly deregulated following PH and SL | 1 | rno-miR-105 | 1,61 | N/A |
2 | rno-miR-466c | 1,53 | HLF, NFIB, HHIP | |
3 | rno-miR-483 | 0,56 | IGF1, SMAD4, DLC1 | |
4 | rno-miR-133b | 0,59 | SP3, MAP3K3, FOXC1 | |
5 | rno-miR-598-5p | 1,4 | N/A | |
B. miRNAs with opposite regulation after PH and SL | 1 | rno-29a | 0,78 | TET1, VEGFA, IGF1 |
C. miRNAs deregulated after SL but not following PH | 1 | rno-miR-708 | 1,55 | NRAS, KRAS, PPARA |
2 | rno-miR-511 | 1,47 | N/A | |
3 | rno-miR-224 | 1,46 | SMAD4, SP7, HOXD10 | |
4 | rno-miR-337 | 1,42 | NLK, MET, CDK6 | |
5 | rno-miR-484 | 0,61 | BCL2, IRS2, PHKB |