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Table 2 Laboratory parameters

From: Acute elevation of intra-abdominal pressure contributes to extravascular shift of fluid and proteins in an experimental porcine model

Parameter

Group

Baseline

60 min

120 min

180 min

240 min

Natrium

C-group

139.4 (1.4)

139.1 (1.5)

139.1 (2.4)

139.1 (2.4)

138.2 (1.4)**

(mmol/l)

P-group

139.0 (1.5)

138.9 (1.8)

138.4 (2.3)

138.0 (3.2)

138.0 (2.1)

Kalium

C-group

4.2 (0.2)

4.4 (0.3)*

4.6 (0.3)**

4.9 (0.3)***

5.3 (0.5)***

(mmol/l)

P-group

4.3 (0.5)

4.5 (0.5)*

5.0 (0.7)**

5.9 (1.2)*

6.1 (0.9)***

Chloride

C-group

99.1 (1.4)

98.6 (0.9)

98.6 (0.9)

99.4 (1.1)

98.6 (1.1)

(mmol/l)

P-group

99.2 (1.3)

98.5 (1.2)

98.6 (2.3)

98.1 (2.0)

98.9 (1.7)

Osmolalitet

C-group

285.8 (2.4)

288.4 (6,6)

283.8 (1.8)

282.8 (3.6)

284.5 (4.9)

(mosm/l)

P-group

282.4 (4.6)

281.9 (2.7)

283.1 (3.6)

284.3 (3.2)

285.9 (4.7)

s-Protein

C-group

47.0 (2.1)

46.4 (2.1)

44.5 (2.1)**

43.4 (1.8)***

43.3 (1.2)**

(g/l)

P-group

46.9 (3.1)

49.3 (3.4)*

47.9 (3.2)

47.9 (4.4)

47.8 (3.6)#

s-Albumin

C-group

31.1 (4.3)

30.9 (4.0)

29.5 (4.3)**

29.8 (3.7)

28.9 (3.4)*

(g/l)

P-group

31.4 (2.9)

32.6 (3.0)

31.9 (2.4)

32.3 (2.4)

32.3 (2.7)

Albuminmass

C-group

2,02 (0.42)

1.98 (0.39)

1.89 (0.37)*

1.93 (0.37)

1.87 (0.41)**

(g/kg)

P-group

1.86 (0.21)

1.76 (0.22)**

1,71 (0.21)***

1.52 (0.21)***

1.45 (0.19)***

Proteinmass

C-group

3.03 (0.3)

2.97 (0.31)

2.84 (0.28)*

2.8 (0.25)*

2.78 (0.32)*

(g/kg)

P-group

2.79 (0.41)

2.67 (0.43)**

2.59 (0.41)***

2.28 (0.43)***

2.16 (0.33)#***

Hemoglobin

C-group

8.0 (0.6)

7.8 (0.6)##

7.9 (0.8)#

7.9 (0.9)###

7.7 (0.8) ###

(g/100 ml)

P-group

8.6 (0.6)

9.1 (0.6)**

9.2 (0.8)**

9.9 (0.6)***

10.1 (0.7)***

pH

C-group

7.50 (0.04)

7.50 (0.03)

7.51 (0.04)

7.50 (0.03)

7.51 (0.02)##

 

P-group

7.52 (0.05)

7.50 (0.04)

7.49 (0.04)

7.45 (0.06)

7.43 (0.05)*

BE

C-group

7.74 (1.5)

8.08 (1.5)

8.31 (1.2)

8.49 (1.1)##

7.81 (1.1)##

(mmol/l)

P-group

7.65 (1.1)

7.36 (1.1)

6.85 (1.0)

5.68 (1.5)

5.29 (1.2)*

P a CO 2

C-group

5.3 (0.5)

5.5 (0.4)

5.3 (0.5)

5.5 (0.5)

5.2 (0.5)#

(kPa)

P-group

5.1 (0.7)

5.3 (0.6)

5.4 (0.4)

5.8 (0.9)

6.2 (0.7)

HCO 3 -

C-group

31.5 (1.4)

31.8 (1.4)

32.1 (1.1)

32.2 (1.0)#

31.6 (0.9)##

(mmol/l)

P-group

31.4 (0.9)

31.2 (1.1)

30.7 (1.0)

29.7 (1.7)

29.1 1.3)*

P a O 2

C-group

34.4 (11.9)

28.1 (5.4)

26.9 (4.0)

26.0 (4.8)

26.2 (5.6)

(kPa)

P-group

25.8 (4.9)

24.7 (4.0)

24.1 (5.5)

24.8 (4.5)

22.7 (5.3)

TNF-α

C-group

72.0 (28.9)

79.5 (27.3)

83.0 (27.0)

77.1 (24.1)

80.7 (29.0)

(pg/ml)

P-group

56.8 (21.1)

63.2(19.4)

64.7 (22.1)

87.8 (29.6)**

91.4 (38.4)*

Interleukin-6

C-group

3.6 (4.7)

9.0 (3.4)**

17.6 (3.4)***

23.9 (8.0)***

30.2 (14.5)**

(pg/ml)

P-group

10.5 (7.8)

16.5 (11.8)**

30.9 (13.1)***

52.8 (26.2)***

83.0 (64.4)

  1. Results as means with SD in parentheses; Control group: C-group; Intervention group: P-group; *:P<0.05 **:P<0.01 ***:P<0.001; within group differences compared with baseline values; #:P<0.05 ##:P<0.01 ###:P<0.001; between group differences, same time.