Virulence Factors | % of virulence genes in AIEC isolates from CD patients (n = 22) | % of virulence genes in non-IBD controls (n = 5) | aP value | |
---|---|---|---|---|
Adhesins | pap A | 0,00% | 0,00% | -- |
pap C | 0,00% | 0,00% | -- | |
pap EF | 0,00% | 0,00% | -- | |
pap G | 0,00% | 0,00% | -- | |
pap G allele II | 13.63% | 0,00% | NS | |
pap G allele III | 0,00% | 0,00% | -- | |
pap G allele II e III | 0,00% | 0,00% | -- | |
sfa/foc DE | 0,00% | 0,00% | -- | |
foc G | 0,00% | 0,00% | -- | |
fim H | 100.00% | 100.00% | NS | |
Afa/Dra BC, | 0,00% | 0,00% | -- | |
nfa E | 0,00% | 0,00% | -- | |
gaf D | 0,00% | 0,00% | -- | |
Capsule | K 1 | 72.72% | 0,00% | 0.013 |
K 5 | 4.54% | 0,00% | NS | |
kps MT II | 72.72% | 0,00% | 0.013 | |
kps MT III | 0,00% | 0,00% | -- | |
rfc | 0,00% | 0,00% | -- | |
Siderophores | fyu A | 72.72% | 0,00% | 0.013 |
iut A | 0,00% | 0,00% | -- | |
Toxins | cnf 1 | 0,00% | 0,00% | -- |
cva C | 0,00% | 0,00% | -- | |
hly A | 0,00% | 0,00% | -- | |
Invasin | ibeA | 81.81% | 0,00% | 0.001 |
Pathogenic island | PAI | 0.00% | 0,00% | -- |
Resistance to serum | tra T | 54.54% | 0,00% | NS |
Transcriptional Activator gene of aggregative adhesion fimbriae | aggR | 4,54% | 0,00% | NS |
CVD432 gene probe sequence of the plasmid of aggregative adhesion | pAA (CVD432) | 0,00% | 0,00% | -- |