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Table 3 Amino acid substitution of the HA ‘Loop’ epitope

From: Genetic characterisation of influenza B viruses detected in Singapore, 2004 to 2009

 

Victoria ‘tip’

 

178

      

185

Yamagata 88

Ë—

D

N

Ë—

K

T

A

T

DSO 010147 2007

Ë—

.

.

Y

.

N

.

.

Vacc0405N 05S B Jilin 20 2003

Ë—

.

.

.

.

N

.

.

Vacc0506N B Jiangsu 10 2003

Ë—

.

.

.

.

N

.

.

Vacc0809NS B Florida 4 2006

Ë—

.

.

.

.

N

.

.

Vacc1213N B Wisconsin 01 2010

Ë—

.

.

Y

.

N

.

.

Singapore 2010-2011

Ë—

.

.

Y

.

N

.

.

B Singapore 04 1991

Ë—

.

.

-

.

.

.

.

B Singapore 11 1994

Ë—

.

.

N

.

.

.

.

B Singapore 22 1998

Ë—

.

.

N

.

.

.

.

B Singapore 31 1998

Ë—

.

.

N

.

.

.

.

B Singapore 35 1998

Ë—

.

.

N

.

.

.

.

B Singapore 222 1979

Ë—

.

Ë—

N

.

.

.

.

B Singapore 1964

Ë—

N

K

N

.

.

.

R

Victoria 87

N

D

N

N

K

T

A

T

DSO Victoria

.

.

.

.

.

.

.

.

DSO 050629 2005

.

.

.

.

.

.

.

.

Vacc04S B Hong Kong 330 2001

.

E

.

.

.

.

.

.

Vacc0608NS B Malaysia 2506 2004

.

.

.

.

.

.

.

.

Vacc0912NS B Brisbane 60 2008

.

.

K

.

.

.

.

.

Singapore 2010-2011

.

.

K

.

.

.

.

.

Lee40

Ë—

.

.

.

.

.

.

I

  1. The ‘Loop’ epitope of the HA protein is the main neutralising epitope of viruses belonging to the Yamagata lineage. Specimens listed under B Yamagata 16 88 belong to the Yamagata lineage while specimens listed under B Victoria 2 87 belong to the Victoria lineage. DSO Victoria: specimens sequenced in this study belonging to the Victoria lineage. Identical amino acids are marked by a dot (.) and deletions are denoted by a dash (−).
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BMC Research Notes

ISSN: 1756-0500

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