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Table 8 Amino acid substitution of the NA calcium binding site

From: Genetic characterisation of influenza B viruses detected in Singapore, 2004 to 2009

 

NA calcium binding site

 

320

329

343

345

B Yamagata 16 1988

E

D

K

R

Rest of DSO Specimens

.

.

.

S

DSO 050528 2005

D

.

.

S

DSO 070214 2006

D

.

.

S

DSO 020114 2007

D

.

.

S

DSO 020132 2007

D

.

.

S

DSO 020147 2007

D

.

.

S

DSO 010147 2007

D

N

.

S

B Singapore 1H 2010

D

.

.

S

B Singapore 32C 2010

D

.

.

S

B Singapore 17H 2010

D

.

.

S

B Singapore 57H 2010

D

.

.

S

B Singapore 65H 2010

D

.

.

S

B Singapore 68C 2010

.

N

E

S

B Singapore 77C 2011

D

.

.

S

B Singapore 71H 2011

D

.

.

S

B Singapore 90C 2011

N

.

.

S

B Singapore 83C 2011

.

N

E

S

B Singapore 87H 2011

.

N

E

S

B Singapore 04 1991

.

.

.

.

B Singapore 11 1994

.

.

.

S

B Singapore 22 1998

.

.

.

S

B Singapore 31 1998

.

.

.

S

B Singapore 35 1991

.

.

.

S

B Singapore 222 1979

.

.

.

L

Vacc04S B Hong Kong 330 2001

.

.

.

S

Vacc0405N 05S B Jilin 20 2003

.

.

.

S

Vacc0405N 05S B Shanghai 361 2002

.

.

.

S

Vacc0608NS B Malaysia 2506 2004

.

.

.

S

Vacc0506N B Jiangsu 10 2003

.

.

.

S

Vacc0809NS B Florida 4 2006

.

N

.

S

Vacc0912NS B Brisbane 60 2008

D

N

.

S

Vacc1213N B Wisconsin 01 2010

.

N

.

S

B Lee 40

K

D

K

L

B Victoria 02 1987

E

D

K

R

  1. 4 amino acid positions within the calcium binding site display variability throughout the NA protein alignment; 320, 329, 343 and 345. Specimens listed under B Yamagata 16 88 belong to the Yamagata. Rest of DSO Specimens: rest of specimens sequenced in this study not individually listed in this table. Identical amino acids are marked by a dot (.).
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BMC Research Notes

ISSN: 1756-0500

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