No. | Dosage | Schedule | Duration of use | Response | PFS |
---|---|---|---|---|---|
1 | 37.5 mg | 4 weeks on/2 weeks off | 1 month | PR | 19 months |
25 mg | 4 weeks on/2 weeks off | 2 months | |||
25 mg | 2 weeks on/1 week off | 21 months | |||
2 | 37.5 mg | 4 weeks on/2 weeks off | 1 month | SD | 9 months |
25 mg | 4 weeks on/2 weeks off | 2 months | |||
25 mg | 2 weeks on/1 week off | 6 months | |||
3 | 37.5 mg | 4 weeks on/2 weeks off | 1 month | PR | 17 months |
25 mg | 2 weeks on/1 week off | 26 months | |||
4 | 37.5 mg | 4 weeks on/2 weeks off | 1 month | PR | 13 months |
25 mg | 4 weeks on/2 weeks off | 3 months | |||
25 mg | 2 weeks on/1 week off | 9 months | |||
5 | 37.5 mg | 4 weeks on/2 weeks off | 1 month | PR | 38 months |
25 mg | 3 weeks on/1 week off | 22 months | |||
25 mg | 2 weeks on/1 week off | 17 months | |||
6 | 37.5 mg | 4 weeks on/2 weeks off | 1 month | PR | 23 months |
25 mg | 4 weeks on/2 weeks off | 5 months | |||
25 mg | 2 weeks on/1 week off | 18 months |