Table 3 Adverse events before and after schedule modification
No. | 25 mg, 4/2 schedule | 25 mg, 2/1 schedule | ||
|---|---|---|---|---|
Grade 2 | Grade 3 | Grade 2 | Grade 3 | |
1 | Fatigue, emesis, leukopenia, neutropenia | None | Emesis, neutropenia | None |
2 | Fatigue, anorexia, dysgeusia, neutropenia, hand-foot syndrome | None | Fatigue, anorexia, dysgeusia, hand-foot syndrome | None |
3 | - | - | Neutropenia | None |
4 | Fatigue, dysgeusia | Proteinuria | Diarrhea | Proteinuria |
5† | Neutropenia | None | None | None |
6 | Anorexia | Fatigue, mucositis, neutropenia | Fatigue | Neutropenia |