Figure 1

Novel hypomorphic alleles of Akt1 ⁺ retain PZ P-element sequences within exon 1. A) Gene map of Akt1 ⁺, transcript variant B (Genbank accession: NM_169707.2). White boxes represent each of the seven exons. The P-element insertion site is located within exon 1 between the transcriptional and translational start sites. B) Molecular characterization confirms the base pair sizes of the internally deleted sections for each hypomorphic allele. Analysis indicates that each allele retains various portions of both the lacZ and rosy genes located either end of the PZ P-element.